cubeConfinableHoming: Inheritance Cube: Confinable Homing

In MGDrivE: Mosquito Gene Drive Explorer

Inheritance Cube: Confinable Homing

Description

This function creates a confinable homing construct, it has 4 alleles at the first locus and 3 alleles at the second.

• W: Wild-type

• H: Homing allele

• A: Antidote allele

• R: No-cost resistance allele

• B: Detrimental resistance allele

Usage

cubeConfinableHoming(
  cF = 1,
  cM = 1,
  chF = 0,
  crF = 0,
  chM = 0,
  crM = 0,
  dR = 0,
  dB = 0,
  crossF = 0,
  crossM = 0,
  eta = NULL,
  phi = NULL,
  omega = NULL,
  xiF = NULL,
  xiM = NULL,
  s = NULL
)

Arguments

cF	Cutting efficiency of drive allele at locus 1 in females
cM	Cutting efficiency of drive allele at locus 1 in males
chF	Homing efficiency of drive allele at locus 1 in females
crF	Resistance allele generation rate at locus 1 in females
chM	Homing efficiency of drive allele at locus 1 in males
crM	Resistance allele generation rate at locus 1 in males
dR	Background mutation rate from W and H into R allele in males and females
dB	Background mutation rate from A into B allele in males and females
crossF	Female crossover rate
crossM	Male crossover rate
eta	Genotype-specific mating fitness
phi	Genotype-specific sex ratio at emergence
omega	Genotype-specific multiplicative modifier of adult mortality
xiF	Genotype-specific female pupatory success
xiM	Genotype-specific male pupatory success
s	Genotype-specific fractional reduction(increase) in fertility

Value

Named list containing the inheritance cube, transition matrix, genotypes, wild-type allele, and all genotype-specific parameters.

MGDrivE documentation built on Sept. 9, 2025, 5:42 p.m.