cubeKillerRescue: Inheritance Cube: Killer-Rescue System

In MGDrivE: Mosquito Gene Drive Explorer

Description

This function creates an inheritance cube to model a Killer-Rescue system. Killer-Rescue is a 2-locus system: one locus has a toxin and the other locus contains the antidote. The loci are assumed independent and are non-homing.
This drive has 3 alleles at locus 1 and 2 alleles and locus 2:

• Locus 1

  • T: Wild-type allele

  • K: "Killer" toxin allele

  • R: Broken toxin allele

• Locus 2

  • W: Wild-type allele

  • A: Antidote allele

Usage

cubeKillerRescue(
  eR = 0,
  Keff = 1,
  Aeff = 1,
  eta = NULL,
  phi = NULL,
  omega = NULL,
  xiF = NULL,
  xiM = NULL,
  s = NULL
)

Arguments

eR	Conversion of K allele to R allele, a basal mutation rate
Keff	Toxin efficacy
Aeff	Antidote efficacy
eta	Genotype-specific mating fitness
phi	Genotype-specific sex ratio at emergence
omega	Genotype-specific multiplicative modifier of adult mortality
xiF	Genotype-specific female pupatory success
xiM	Genotype-specific male pupatory success
s	Genotype-specific fractional reduction(increase) in fertility

Value

Named list containing the inheritance cube, transition matrix, genotypes, wild-type allele, and all genotype-specific parameters.

MGDrivE documentation built on Oct. 23, 2020, 7:28 p.m.