MWUMrs: Identifies cluster specific master regulators using the...

View source: R/mr_funcs.R

MWUMrsR Documentation

Identifies cluster specific master regulators using the Mann-Whitney U-test. Approximates p-vals using a normal distribution for n > 30.

Description

Identifies cluster specific master regulators using the Mann-Whitney U-test. Approximates p-vals using a normal distribution for n > 30.

Usage

MWUMrs(dat.object, clust.vect)

Arguments

dat.object

Seurat object w/ PISCES assay and viper matrix in 'scale.data'.

clust.vect

Vector of cluster labels; if not specified, will use 'PISCES;misc$pisces.cluster' as the cluster labels

Value

List of log p-values for pos/neg MRs in each cluster; stored in PISCES assay under 'misc' as 'mwuMRs'


califano-lab/PISCES documentation built on Jan. 11, 2023, 5:34 a.m.