cubeXHomingDeposition: Inheritance Cube: CRISPR (Clustered Regularly Interspaced...

In MGDrivE: Mosquito Gene Drive Explorer

Inheritance Cube: CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) X-linked with 2 Resistance Allele and Maternal Deposition

Description

This is an X-linked version of the 2 allele cube. It assumes that the construct is on the X chromosome and there is no male homing. It also has maternal deposition, i.e., when the male provides a W allele to a female with an H allele, some portion are cut during oogenesis. If the deposition parameters are zero (*D parameters), this is just an X-linked drive.

Usage

cubeXHomingDeposition(
  cF = 1,
  chF = 0,
  crF = 0,
  dF = 0,
  dhF = 0,
  drF = 0,
  eta = NULL,
  phi = NULL,
  omega = NULL,
  xiF = NULL,
  xiM = NULL,
  s = NULL
)

Arguments

cF	Female cutting rate
chF	Female proper homing rate
crF	Female no-cost resistance generation rate
dF	Female deposition cutting rate
dhF	Female deposition proper homing rate
drF	Female deposition no-cost resistance generation rate
eta	Genotype-specific mating fitness
phi	Genotype-specific sex ratio at emergence
omega	Genotype-specific multiplicative modifier of adult mortality
xiF	Genotype-specific female pupatory success
xiM	Genotype-specific male pupatory success
s	Genotype-specific fractional reduction(increase) in fertility

Value

Named list containing the inheritance cube, transition matrix, genotypes, wild-type allele, and all genotype-specific parameters.

MGDrivE documentation built on Sept. 9, 2025, 5:42 p.m.