undirected_nes: Computes the Undirected NES

In califano-lab/PISCES: Protein Activity Inferecne in Single Cells

Computes the Undirected NES

Description

Computes the Undirected NES

Usage

undirected_nes(R, S, AW.AM.abs.prod, E.r, E.r2, n)

Arguments

R	Rank normalized ges matrix (genes x samples).
S	Sign of ges matrix (genes x samples).
AW.AM.abs.prod	Product of the association weight (AW) and absolute value of the association mode (AM.abs) matrices created from the regulon list.
E.r	Expected value of r in each sample (scalar value).
E.r2	Expected value of r^2 in each sample (scalar value).
n	Number of samples (scalar value).

Value

List of matrices, each (regulons x samples): Enrichment score matrix 'es'; expected value 'exp'; variance 'var'; NES matrix 'NES'

califano-lab/PISCES documentation built on Jan. 11, 2023, 5:34 a.m.