ANOVA.Repeat.Measure: ANOVA with Repeat Measures

In TrialSize: R Functions for Chapter 3,4,6,7,9,10,11,12,14,15 of Sample Size Calculation in Clinical Research

Description

The study has multiple assessments in a parallel-group clinical trial. α_i is the fixed effect for the ith treatment ∑ α_i =0.

Ho: α_{i} = α_{i'}

Ha: not equal

Usage

ANOVA.Repeat.Measure(alpha, beta, sigma, delta, m)

Arguments

alpha	significance level
beta	power = 1-beta
sigma	sigma^2 is the sum of the variance components.
delta	a clinically meaningful difference
m	Bonferroni adjustment for alpha, totally m pairs comparison.

References

Chow SC, Shao J, Wang H. Sample Size Calculation in Clinical Research. New York: Marcel Dekker, 2003

Examples

Example.15.3.4<-ANOVA.Repeat.Measure(0.05,0.2,1.25,1.5,3)
Example.15.3.4
# 15

Example output

[1] 14.54044

TrialSize documentation built on July 8, 2020, 7:19 p.m.