Cox.Equality: Test for equality in Cox PH model.

In TrialSize: R Functions for Chapter 3,4,6,7,9,10,11,12,14,15 of Sample Size Calculation in Clinical Research

Description

b is the log hazard ratio for treatment, b0 is the log hazard ratio for the controls

H0: b=b0

Ha: not equal to b0

The test is finding whether there is a difference between the hazard rates of the treatment and control.

Usage

Cox.Equality(alpha, beta, loghr, p1,d)

Arguments

alpha	significance level
beta	power = 1-beta
loghr	log hazard ratio=log(lamda2/lamda1)=b
p1	the proportion of patients in treatment 1 group
d	the probability of observing an event

References

Chow SC, Shao J, Wang H. Sample Size Calculation in Clinical Research. New York: Marcel Dekker, 2003

Examples

Example.7.3.4<-Cox.Equality(0.05,0.2,log(2),0.5,0.8)
Example.7.3.4

TrialSize documentation built on July 8, 2020, 7:19 p.m.