Cox.Equality | R Documentation |
b is the log hazard ratio for treatment, b0 is the log hazard ratio for the controls
H0: b=b0
Ha: not equal to b0
The test is finding whether there is a difference between the hazard rates of the treatment and control.
Cox.Equality(alpha, beta, loghr, p1,d)
alpha |
significance level |
beta |
power = 1-beta |
loghr |
log hazard ratio=log(lamda2/lamda1)=b |
p1 |
the proportion of patients in treatment 1 group |
d |
the probability of observing an event |
Chow SC, Shao J, Wang H. Sample Size Calculation in Clinical Research. New York: Marcel Dekker, 2003
Example.7.3.4<-Cox.Equality(0.05,0.2,log(2),0.5,0.8)
Example.7.3.4
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