Cochran.Armitage.Trend: Cochran-Armitage's Test for Trend

In TrialSize: R Functions for Chapter 3,4,6,7,9,10,11,12,14,15 of Sample Size Calculation in Clinical Research

Description

H0: p0=p1=p2=...=pK

Ha: p0 <= p1 <= p2 <=...<= pK with p0 < pK

Usage

Cochran.Armitage.Trend(alpha, beta, pi, di, ni, delta)

Arguments

alpha	significance level
beta	power = 1-beta
pi	pi is the response rate in ith group.
di	di is the dose level
ni	ni is the sample size for group i
delta	delta is the clinically meaningful minimal difference

References

Chow SC, Shao J, Wang H. Sample Size Calculation in Clinical Research. New York: Marcel Dekker, 2003

Examples

pi=c(0.1,0.3,0.5,0.7);
di=c(1,2,3,4);
ni=c(10,10,10,10);

Example.11.5<-Cochran.Armitage.Trend(alpha=0.05,beta=0.2,pi=pi,di=di,ni=ni,delta=1)
Example.11.5
# 7.5 for one group. Total 28-32. 

TrialSize documentation built on July 8, 2020, 7:19 p.m.