Test for Equality of Inter-Subject Variabilities

Description

H0: between-subject variance of treatment T is equal to between-subject variance of treatment R

Ha: not equal

The test is finding whether two drug products have the same inter-subject variability.

Usage

1
InterSV.Equality(alpha, beta, vbt, vwt, vbr, vwr, m)

Arguments

alpha

significance level

beta

power = 1-beta

vbt

between-subject variance of treatment T

vwt

within-subject variance of treatment T

vbr

between-subject variance of treatment R

vwr

within-subject variance of treatment R

m

for each subject, there are m replicates.

References

Chow SC, Shao J, Wang H. Sample Size Calculation in Clinical Research. New York: Marcel Dekker, 2003

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