QOL: Quality of life

In TrialSize: R Functions for Chapter 3,4,6,7,9,10,11,12,14,15 of Sample Size Calculation in Clinical Research

Quality of life

Description

Under the time series model, determine sample size based on normal approximation.

Usage

QOL(alpha, beta, c, epsilon)

Arguments

alpha	significance level
beta	power = 1-beta
c	constant c=0.5
epsilon	a meaningful difference epsilon. If the chosen acceptable limits are (-\delta, \delta). epsilon=\delta-\eta, \eta is the measure for detecting an equivalence when the true difference in treatment means is less than a small constant \eta.

References

Chow SC, Shao J, Wang H. Sample Size Calculation in Clinical Research. New York: Marcel Dekker, 2003

Examples

Example.15.4.3<-QOL(0.05,0.1,0.5,0.25)
Example.15.4.3

TrialSize documentation built on April 12, 2025, 2:01 a.m.