RelativeRisk.Equivalence: Relative Risk in Parallel Design test for Equivalence

In TrialSize: R Functions for Chapter 3,4,6,7,9,10,11,12,14,15 of Sample Size Calculation in Clinical Research

Relative Risk in Parallel Design test for Equivalence

Description

Ho: |log(OR)| \ge margin

Ha: |log(OR)| < margin

Usage

RelativeRisk.Equivalence(alpha, beta, or, k, pt, pc, margin)

Arguments

alpha	significance level
beta	power = 1-beta
or	or=pt(1-pc)/pc(1-pt)
k	k=nT/nC
pt	the probability of observing an outcome of interest for a patient treatment by a test treatment
pc	the probability of observing an outcome of interest for a patient treatment by a control
margin	the superiority or non-inferiority margin

References

Chow SC, Shao J, Wang H. Sample Size Calculation in Clinical Research. New York: Marcel Dekker, 2003

Examples

Example.4.6.4<-RelativeRisk.Equivalence(0.05,0.2,2,1,0.25,0.25,.5)
Example.4.6.4

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