RelativeRisk.NIS: Relative Risk in Parallel Design test for...

In TrialSize: R Functions for Chapter 3,4,6,7,9,10,11,12,14,15 of Sample Size Calculation in Clinical Research

Relative Risk in Parallel Design test for Non-inferiority/Superiority

Description

Ho: OR \le margin

Ha: OR > margin

Usage

RelativeRisk.NIS(alpha, beta, or, k, pt, pc, margin)

Arguments

alpha	significance level
beta	power = 1-beta
or	or=pt(1-pc)/pc(1-pt)
k	k=nT/nC
pt	the probability of observing an outcome of interest for a patient treatment by a test treatment
pc	the probability of observing an outcome of interest for a patient treatment by a control
margin	the superiority or non-inferiority margin

References

Chow SC, Shao J, Wang H. Sample Size Calculation in Clinical Research. New York: Marcel Dekker, 2003

Examples

Example.4.6.4<-RelativeRisk.NIS(0.05,0.2,2,1,0.4,0.25,.2)
Example.4.6.4

TrialSize documentation built on April 12, 2025, 2:01 a.m.