View source: R/TwoSampleProportion.Equivalence.R
TwoSampleProportion.Equivalence | R Documentation |
Ho: |p1-p2| \ge margin
Ha: |p1-p2| < margin
The proportion of response p1 is equivalent to the reference drug p2 is the null hypothesis is rejected
TwoSampleProportion.Equivalence(alpha, beta, p1, p2, k, delta, margin)
alpha |
significance level |
beta |
power = 1-beta |
p1 |
the mean response rate for test drug |
p2 |
the rate for reference drug |
k |
k=n1/n2 |
delta |
delta=p1-p2 |
margin |
the superiority or non-inferiority margin |
Chow SC, Shao J, Wang H. Sample Size Calculation in Clinical Research. New York: Marcel Dekker, 2003
Example.4.2.4<-TwoSampleProportion.Equivalence(0.05,0.2,0.75,0.8,1,0.2,0.05)
Example.4.2.4
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