TwoSampleSeqCrossOver.NIS: Two sample proportion Crossover design for...

In TrialSize: R Functions for Chapter 3,4,6,7,9,10,11,12,14,15 of Sample Size Calculation in Clinical Research

Two sample proportion Crossover design for Non-inferiority/Superiority

Description

H0: p2-p1 <= margin

Ha: p2-p1 > margin

Usage

TwoSampleSeqCrossOver.NIS(alpha, beta, sigma, sequence, delta, margin)

Arguments

alpha	significance level
beta	power = 1-beta
sigma	standard deviation in crossover design
sequence	total sequence number
delta	the superiority or non-inferiority margin
margin	margin=p2-p1

References

Chow SC, Shao J, Wang H. Sample Size Calculation in Clinical Research. New York: Marcel Dekker, 2003

Examples

Example.4.3.4<-TwoSampleSeqCrossOver.NIS(0.05,0.2,0.25,2,0,-0.2)
Example.4.3.4

TrialSize documentation built on April 12, 2025, 2:01 a.m.