TwoSampleSurvival.Conditional: Test for two sample conditional data in exponential model for...

In TrialSize: R Functions for Chapter 3,4,6,7,9,10,11,12,14,15 of Sample Size Calculation in Clinical Research

Test for two sample conditional data in exponential model for survival data

Description

unconditional versus conditional

Usage

TwoSampleSurvival.Conditional(alpha,beta,lam1,lam2,eta1,eta2,k,ttotal,taccrual,g1,g2)

Arguments

alpha	significance level
beta	power = 1-beta
lam1	the hazard rates of control group
lam2	the hazard rates of a test drug
eta1	in control group, the losses are exponentially distributed with loss hazard rate eta1
eta2	in treatment group, the losses are exponentially distributed with loss hazard rate eta2
k	k=n1/n2 sample size ratio
ttotal	Total trial time
taccrual	accrual time period
g1	parameter for the entry distribution of control group, which is uniform patient entry with gamma1=0.
g2	parameter for the entry distribution of treatment group, which is uniform patient entry with gamma2=0.

References

Chow SC, Shao J, Wang H. Sample Size Calculation in Clinical Research. New York: Marcel Dekker, 2003

TrialSize documentation built on April 12, 2025, 2:01 a.m.