WilliamsDesign.Equivalence: Williams Design test for equivalence

In TrialSize: R Functions for Chapter 3,4,6,7,9,10,11,12,14,15 of Sample Size Calculation in Clinical Research

Williams Design test for equivalence

Description

Ho: |\mu_2-\mu_1| \ge margin

Ha: |\mu_2-\mu_1| < margin

Usage

WilliamsDesign.Equivalence(alpha, beta, sigma, sequence, delta, margin)

Arguments

alpha	significance level
beta	power = 1-beta
sigma	standard deviation in crossover design
sequence	total sequence number
delta	the superiority or non-inferiority margin
margin	margin=\mu_{1}-\mu_{2}

References

Chow SC, Shao J, Wang H. Sample Size Calculation in Clinical Research. New York: Marcel Dekker, 2003

Examples

Example.4.5.4<-WilliamsDesign.Equivalence(0.05,0.2,0.75^2,6,0.2,0.3)
Example.4.5.4

TrialSize documentation built on April 12, 2025, 2:01 a.m.