Files in httk

High-Throughput Toxicokinetics

NEWS.md README.md R/calc_analytic_css_1comp.R R/calc_analytic_css_3comp.R R/get_lit_cheminfo.R R/calc_hep_clearance.R R/calc_kair.R R/gen_age_height_weight.R R/modelinfo_schmitt.R R/ckd_epi_eq.R R/modelinfo_3compss.R R/propagate_invitrouv_3comp.R R/calc_maternal_bw.R R/httkpop_direct_resample_inner.R R/onAtttach.R R/httkpop_biotophys_default.R R/tissue_scale.R R/calc_tkstats.R R/get_clint.R R/get_fup.R R/scale_dosing.R R/calc_hep_fu.R R/calc_krbc2pu.R R/add_chemtable.R R/convert_units.R R/inhalation_inits.R R/httkpop_virtual_indiv.R R/get_lit_css.R R/calc_css.R R/calc_analytic_css.R R/do_initial_dose_pbtk.R R/export_pbtk_jarnac.R R/calc_half_life.R R/get_weight_class.R R/load_honda2023.R R/get_lit_oral_equiv.R R/calc_timecourse_peak.R R/calc_mc_tk.R R/get_cheminfo.R R/calc_mc_oral_equiv.R R/honda.ivive.R R/httkpop_mc.R R/predict_partitioning_schmitt.R R/set_httk_precision.R R/tissue_masses_flows.R R/ionization_functions.R R/data.R R/modelinfo_1comp.R R/gen_height_weight.R R/age_draw_smooth.R R/solve_model.R R/check_model.R R/tissue_mass_functions.R R/armitage.R R/parameterize_gas_pbtk.R R/get_param.r R/httkpop_direct_resample.R R/monte_carlo.R R/get_rblood2plasma.R R/parameterize_3comp.R R/httk-package.R R/propagate_invitrouv_pbtk.R R/solve_fetal_pbtk.R R/rmed0non0u95.R R/solve_gas_pbtk.R R/parameterize_1comp.R R/available_rblood2plasma.R R/calc_elimination_rate.R R/in.list.R R/reset_httk.R R/create_mc_samples.R R/httkpop_generate.R R/calc_total_clearance.R R/estimate_hematocrit.R R/benchmark_httk.R R/modelinfo_pbtk.R R/lump_tissues.R R/invitro_mc.R R/calc_analytic_css_pbtk.R R/estimate_gfr_ped.R R/parameterize_schmitt.R R/solve_pbtk.R R/solve_1comp.R R/get_chem_id.R R/estimate_gfr.R R/get_physchem_param.R R/calc_analytic_css_3compss.R R/parameterize_steadystate.R R/zzz.R R/load_pradeep2020.R R/calc_hep_bioavailability.R R/gen_serum_creatinine.R R/globals.R R/load_sipes2017.R R/load_dawson2021.R R/apply_fup_adjustment.R R/calc_oral_bioavailability.R R/calc_mc_css.R R/convert_solve_x.R R/hematocrit_infants.R R/get_gfr_category.R R/solve_3comp.R R/calc_fetal_phys.R R/parameterize_pbtk.R R/r_left_censored_norm.R R/calc_ma.R R/apply_clint_adjustment.R R/modelinfo_gas_pbtk.R R/calc_volume_of_distribution.R R/calc_fup_correction.R R/export_pbtk_sbml.R R/get_invitroPK_param.R R/modelinfo_3comp.R R/modelinfo_fetal_pbtk.R R/get_fbio.R R/calc_rblood2plasma.R R/propagate_invitrouv_1comp.R R/get_caco2.R R/utils.R R/parameterize_fetal_pbtk.R inst/doc/Vh_Linakis2020.R inst/doc/Vf_Honda2019.R inst/doc/V1_IntroToHTTK.R inst/doc/Vd_Frank2019.Rmd inst/doc/Vi_Kapraun2022.R inst/doc/Vb_Ring2017.R inst/doc/Vd_Frank2019.R inst/doc/Vc_Pearce2017.Rmd inst/doc/Ve_Wambaugh2018.Rmd inst/doc/Vc_Pearce2017.R inst/doc/Vf_Honda2019.Rmd inst/doc/V1_IntroToHTTK.Rmd inst/doc/V2_IntrotoIVIVE.Rmd inst/doc/Vh_Linakis2020.Rmd inst/doc/V2_IntrotoIVIVE.R inst/doc/Vg_Wambaugh2019.Rmd inst/doc/Ve_Wambaugh2018.R inst/doc/Vi_Kapraun2022.Rmd inst/doc/Vb_Ring2017.Rmd inst/doc/Vg_Wambaugh2019.R inst/doc/Va_Pearce2017.R inst/doc/Va_Pearce2017.Rmd tests/cheminfo_test.R tests/adddata_test.R tests/3compss_test.R tests/ivive_test.R tests/fetal_pbtk_testing.R tests/solve_gas_test.R tests/1comp_test.R tests/caco2_test.R tests/pbtk_test.R tests/3comp_test.R tests/montecarlo_tests.R tests/other_tests.R tests/unit_test.R vignettes/Vd_Frank2019.Rmd vignettes/Vc_Pearce2017.Rmd vignettes/Ve_Wambaugh2018.Rmd vignettes/Vf_Honda2019.Rmd vignettes/V1_IntroToHTTK.Rmd vignettes/V2_IntrotoIVIVE.Rmd vignettes/Vh_Linakis2020.Rmd vignettes/Vg_Wambaugh2019.Rmd vignettes/Vi_Kapraun2022.Rmd vignettes/Vb_Ring2017.Rmd vignettes/Va_Pearce2017.Rmd man/armitage_estimate_sarea.Rd man/get_physchem_param.Rd man/httk.performance.Rd man/benchmark_httk.Rd man/supptab1_Linakis2020.Rd man/get_weight_class.Rd man/pharma.Rd man/metabolism_data_Linakis2020.Rd man/parameterize_1comp.Rd man/gen_serum_creatinine.Rd man/httkpop_direct_resample_inner.Rd man/calc_half_life.Rd man/pksim.pcs.Rd man/calc_tkstats.Rd man/load_dawson2021.Rd man/calc_elimination_rate.Rd man/calc_rblood2plasma.Rd man/wambaugh2019.tox21.Rd man/howgate.Rd man/chem.physical_and_invitro.data.Rd man/convert_solve_x.Rd man/hematocrit_infants.Rd man/bmiage.Rd man/gen_age_height_weight.Rd man/calc_mc_oral_equiv.Rd man/blood_mass_correct.Rd man/hw_H.Rd man/spleen_mass_children.Rd man/httkpop_generate.Rd man/reset_httk.Rd man/augment.table.Rd man/skin_mass_bosgra.Rd man/calc_hep_fu.Rd man/honda.ivive.Rd man/httkpop.Rd man/honda2023.qspr.Rd man/calc_css.Rd man/lung_mass_children.Rd man/skeletal_muscle_mass_children.Rd man/parameterize_schmitt.Rd man/wang2018.Rd man/get_lit_css.Rd man/get_lit_oral_equiv.Rd man/Obach2008.Rd man/kidney_mass_children.Rd man/EPA.ref.Rd man/calc_hep_bioavailability.Rd man/estimate_hematocrit.Rd man/sipes2017.Rd man/CAS.checksum.Rd man/propagate_invitrouv_1comp.Rd man/body_surface_area.Rd man/age_draw_smooth.Rd man/get_cheminfo.Rd man/well_param.Rd man/calc_mc_tk.Rd man/httkpop_direct_resample.Rd man/invitro_mc.Rd man/calc_analytic_css_3compss.Rd man/get_caco2.Rd man/estimate_gfr.Rd man/get_invitroPK_param.Rd man/calc_krbc2pu.Rd man/blood_weight.Rd man/calc_maternal_bw.Rd man/concentration_data_Linakis2020.Rd man/rmed0non0u95.Rd man/get_wetmore_cheminfo.Rd man/solve_pbtk.Rd man/available_rblood2plasma.Rd man/honda2023.data.Rd man/hct_h.Rd man/create_mc_samples.Rd man/calc_fup_correction.Rd man/propagate_invitrouv_3comp.Rd man/physiology.data.Rd man/rfun.Rd man/chem.invivo.PK.data.Rd man/set_httk_precision.Rd man/kapraun2019.Rd man/export_pbtk_jarnac.Rd man/calc_stats.Rd man/get_fup.Rd man/brain_mass.Rd man/wambaugh2019.Rd man/get_wetmore_oral_equiv.Rd man/get_clint.Rd man/get_rblood2plasma.Rd man/calc_hepatic_clearance.Rd man/supptab2_Linakis2020.Rd man/onlyp.Rd man/calc_analytic_css_3comp.Rd man/pradeep2020.Rd man/example.toxcast.Rd man/pregnonpregaucs.Rd man/load_pradeep2020.Rd man/calc_dow.Rd man/solve_1comp.Rd man/mecdt.Rd man/pc.data.Rd man/liver_mass_children.Rd man/get_wetmore_css.Rd man/bone_mass_age.Rd man/solve_gas_pbtk.Rd man/calc_fbio.oral.Rd man/is.httk.Rd man/load_sipes2017.Rd man/apply_fup_adjustment.Rd man/tissue_masses_flows.Rd man/calc_total_clearance.Rd man/wambaugh2019.seem3.Rd man/wambaugh2019.raw.Rd man/fetalpcs.Rd man/httkpop_biotophys_default.Rd man/lump_tissues.Rd man/parameterize_pbtk.Rd man/calc_analytic_css_pbtk.Rd man/calc_fetal_phys.Rd man/dawson2021.Rd man/scale_dosing.Rd man/apply_clint_adjustment.Rd man/get_lit_cheminfo.Rd man/load_honda2023.Rd man/tissue.data.Rd man/johnson.Rd man/add_chemtable.Rd man/skeletal_muscle_mass.Rd man/mcnally_dt.Rd man/aylward2014.Rd man/pancreas_mass_children.Rd man/is_in_inclusive.Rd man/get_gfr_category.Rd man/Tables.Rdata.stamp.Rd man/gen_height_weight.Rd man/solve_model.Rd man/wambaugh2019.nhanes.Rd man/solve_fetal_pbtk.Rd man/calc_analytic_css_1comp.Rd man/export_pbtk_sbml.Rd man/tissue_scale.Rd man/in.list.Rd man/calc_vdist.Rd man/wfl.Rd man/Frank2018invivo.Rd man/calc_kair.Rd man/calc_analytic_css.Rd man/Wetmore2012.Rd man/check_model.Rd man/estimate_gfr_ped.Rd man/parameterize_gas_pbtk.Rd man/chem.invivo.PK.aggregate.data.Rd man/calc_hep_clearance.Rd man/solve_3comp.Rd man/parameterize_fetal_pbtk.Rd man/predict_partitioning_schmitt.Rd man/calc_mc_css.Rd man/convert_units.Rd man/chem.invivo.PK.summary.data.Rd man/httk-package.Rd man/r_left_censored_norm.Rd man/httkpop_virtual_indiv.Rd man/armitage_input.Rd man/calc_ma.Rd man/get_chem_id.Rd man/example.seem.Rd man/get_fbio.Rd man/parameterize_3comp.Rd man/httkpop_mc.Rd man/scr_h.Rd man/parameterize_steadystate.Rd man/ckd_epi_eq.Rd man/calc_ionization.Rd man/monte_carlo.Rd man/pearce2017regression.Rd man/armitage_eval.Rd man/propagate_invitrouv_pbtk.Rd man/figures/ivive.pdf man/figures/pbtk.pdf man/figures/gaspbtk.pdf man/figures/1comp.pdf man/figures/3comp.pdf